Relationship of α-MSH and AgRP axons to the perikarya of melanocortin-4 receptor neurons.

Leandro B Lima,João A B Pedroso,Martin Metzger,Laurent Gautron,Jose Donato

Brain Research（2019）

引用 10|浏览16

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摘要

•AgRP and POMC terminals project to an identical set of brain nuclei.•Several brain regions exhibit AgRP and α-MSH terminals, but do not express MC4R.•Other areas contain MC4R cells and receive no innervation of AgRP and POMC neurons.•The amount of AgRP and POMC presumptive appositions on MC4R soma is area-specific.•Several brain regions receive more AgRP appositions than α-MSH appositions on MC4R soma.

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关键词

α-MSH,AA,Aco,AgRP,ARH,BLA,BST,CA,CG,CMS,CnF,D3V,DMH,DMTg,DpG,DR,EAM,GABA,GFP,Gi,IEn,IP,LC,LDTg,LH,LHb,LPAG,LSI,MC4R,MCPO,MD,MdD,MnPO,MPA,MPT,Pa,Pa,PeF,PF,PGMC,PH,PMD,PMnR,PnC,POMC,Pr5,PrC,PT,PV,Re,RML,SoL,STMV,VPPC,ZI

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