Comparison of Gene Expression in Cynomolgus Monkeys with Preclinical Type II Diabetes Induced by Different High Energy Diets

Li-Sha Jin,Jun-Hua Rao,Li-Biao Zhang,Fang Ji,Yan-Chun Zhang,Xiang-Fen Hao,Bai-Lu Peng,Xiao-Ming Liu,Yun-Xiao Sun

Animal models and experimental medicine（2019）

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摘要

Cynomolgus disease models that are similar to the preclinical stage of human type 2 diabetes mellitus (T2DM) were established by feeding middle‐aged cynomolgus monkeys different high energy diets to study the differential expression of diabetes‐related genes.

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关键词

cynomolgus monkey,gene expression,high energy diet,preclinical phase,type 2 diabetes

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