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RNase L Facilitates the Repair of DNA Double-Strand Breaks through the Nonhomologous End-Joining Pathway.

FEBS LETTERS, no. 11 (2019): 1190-1200

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Abstract

RNA molecules have been found to play important roles in DNA double-strand break (DSB) repair, but the exact underlying mechanism remains unclear. Here, we aimed to clarify the function of RNase L, an important ribonuclease in the immune system of vertebrates, in DSB repair. Knockdown of RNase L reduces cell survival after induction of DS...More

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Yiran Zhong
Yiran Zhong
Bingxin Pan
Bingxin Pan
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