Kurze Peptide regulieren die Aktivität bakterieller Ribosomen

In all living cells ribosomes are responsible for the translation of genetic information into the corresponding protein sequence. This central position does not only make them a valuable target for antibiotics but also offers great possibilities to regulate gene expression. This article addresses two distinct mechanisms of ribosomal activity regulation: via short nascent peptides (regulation in cis) and via proline-rich antimicrobial peptides (regulation in trans).