Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma.
Brain, Behavior, and Immunity(2019)
摘要
•Psychosocial stress causes structural cardiac damage in male mice.•Stress-induced structural cardiac changes are accompanied by functional deficits.•Stress-induced cytokines affect cardiomyocytes structure and function in vitro.•Sensory contact to aggressor delays structural and functional cardiac recovery.•Individual housing promotes cardiac recovery but aggravates behavioral deficits.
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关键词
Chronic psychosocial trauma,Chronic subordinate colony housing,Posttraumatic stress disorder,Cardiac damage,Sensory contact,Social anxiety
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