Back Cover: Asymmetric Synthesis of Chiral α -Substituted Mercaptoglycine Derivatives via α -Sulfenylation of Ni(II) Complex of Glycine and S -Substituted 4-Methylbenzenesulfonothioate (Chin. J. Chem. 9/2017)

The back cover picture shows the asymmetric synthesis of α-substituted mercaptoglycine via nickel(II) complex. The α-substituted mercaptoglycine is an important framework of various peptide drugs and nickel(II) complex can be utilized to generate single enantiomer of α-substituted amino acid efficiently. This work establishes an efficient method to access α-substituted mercaptoglycine with good yield and high stereoselectivity, which can promote the design of new peptide drugs in a broad scope. More details are discussed in the article by Wang et al. on page 1383-1390.