Stereoselective synthesis of (−)-synargentolide B

Tetrahedron Letters(2018)

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摘要
•A concise synthesis of unnatural synargentolide B has been accomplished in 10 steps.•Abundantly available l-arabinose and d-ethyl lactate was used as chiral template.•The key steps include olefin CM reaction and one-pot deprotection-lactonization.
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