Concordance Between Rtog And Eortc Risk Factors In Low Grade Gliomas: Who Will Remain Standing In The Ring At Bell'S Sound?

2040Background: Low grade gliomas (LGG) are a heterogeneous group of brain primary tumors. The EORTC and the RTOG criteria are the most valuable scores to evaluate risk factors and for treatment decision. However, there is no data about concordance between criteria. Methods: We conducted an analysis on LGG patients treated in our Institution from 1998 to 2015. The population was stratified by RTOG criteria and whenever feasible we assessed the risk using both RTOG and EORTC criteria. Results: Median follow up (mFU) was 78.6 months. We evaluated 204 patients with histologically diagnosed LGG. All the patients were stratified by RTOG criteria and a subgroup of 51 patients by both RTOG and EORTC criteria. The univariate analysis showed a statistically significant difference according to RTOG criteria (p = 0.01) for both OS and PFS. Low risk patients had a better OS compared to high risk group (211.0 vs 145.5 months, p = 0.01) and a longer PFS (60.0 vs 39.8 months, p = 0.005). The multivariate analysis confir...