Rapamycin Nanoparticles Potently Induce Cardiac Autophagy and Improve Ventricular Function in 18-month Old mdx Mice, The Animal Model of Duchenne Muscular Dystrophy

INTRODUCTION: Autophagy, or “self-eating”, is a cellular process responsible for recycling metabolites and eliminating toxic byproducts. We have shown previously that rapamycin-loaded nanoparticles...