Impact of genetic studies on comprehension and treatment of congenital heart disease

Tatiana Alicandro,Carolina Putotto,Giulio Calcagni,Marta Unolt,Gioia Mastromoro,Maria Cristina Digilio,Paolo Versacci,Bruno Marino

Progress in Pediatric Cardiology（2018）

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摘要

The great impact of genetic factors in the field of congenital heart disease (CHD) was highlighted about 30 years ago by the Baltimore-Washington Infant Study. Moreover, recent genetic studies have shown their importance not only in detecting the cause of some heart malformations, but also in improving their treatment and prognosis.

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关键词

Congenital heart defects,Genetic syndromes,CNV,Prognosis,Personalized medicine

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