Sensing carboxylesterase 1 in living systems by a practical and isoform-specific fluorescent probe

Lele Ding,Zhenhao Tian,Jie Hou,Tongyi Dou,Qiang Jin,Dandan Wang,Liwei Zou,Yadi Zhu,Yunqing Song,Jingnan Cui,Guangbo Ge

Chinese Chemical Letters（2019）

引用 26|浏览11

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摘要

A practical and isoform-specific fluorescent probe based on BIDIPY dye have been designed, synthesized and well characterized for sensing CES1 activities in various biological systems such as living cells, tissues and zebrafish.

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关键词

Carboxylesterase 1,Fluorescent probe,Biological imaging,Living cells based inhibitors screening,BODIPY dyes

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