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Dysregulated mitochondrial integrity associated with lamin B1 reduction is involved in cellular senescence progression in COPD pathogenesis

Nayuta Saito,Jun Araya,Saburo Ito,Yusuke Hosaka,Tsukasa Kadota,Masahiro Yoshida,Kazuya Tsubouchi,Akihiro Ichikawa,Yusuke Kurita,Kenji Kobayashi,Shunsuke Minagawa,Hiromichi Hara,Hirofumi Utsumi,Haruhiko Yanagisawa,Mitsuo Hashimoto,Hiroshi Wakui,Takeo Ishikawa,Takanori Numata,Yumi Kaneko,Katsutoshi Nakayama,Kazuyoshi Kuwano

EUROPEAN RESPIRATORY JOURNAL（2018）

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Key words
dysregulated mitochondrial integrity,cellular senescence progression,lamin b1 reduction,pathogenesis
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