Quality of life is associated with increased symptom burden and markers of disease severity: data from the German Bronchiectasis Registry PROGNOSIS

We investigated associations between the Quality of Life Questionnaire-Bronchiectasis (QoL-B) scales and symptom burden as well as markers of disease severity within the German Bronchiectasis Registry PROGNOSIS. The German translation of the QoL-B V.3.0, which uses 8 scales (Respiratory Symptoms [RS], Physical Functioning [PF], Vitality [V], Role Functioning [RF], Health Perceptions [HP], Emotional Functioning [EF], Social Functioning [SF] and Treatment Burden [TB]), is routinely applied at baseline. Between Jun 2015 and Feb 2018, 1043 subjects were recruited from 38 centers (median age 61 years, 59% female). At baseline, up to 95% of subjects completed the QoL-B. All scales were significantly associated with higher MRC dyspnea scores (p Our analysis confirms that the QoL-B is a feasible tool to determine quality of life in this representative cohort of German patients with bronchiectasis.