LRSAM1 E3 ubiquitin ligase: molecular neurobiological perspectives linked with brain diseases
Cellular and Molecular Life Sciences, pp. 2093-2110, 2019.
LRSAM1 Chaperone Misfolded proteins Neurodegeneration
Cellular protein quality control (PQC) plays a significant role in the maintenance of cellular homeostasis. Failure of PQC mechanism may lead to various neurodegenerative diseases due to accumulation of aberrant proteins. To avoid such fatal neuronal conditions PQC employs autophagy and ubiquitin proteasome system (UPS) to degrade misfold...More
Full Text (Upload PDF)
PPT (Upload PPT)