Pd47-01 bms-986205, an indoleamine 2,3-dioxygenase 1 inhibitor, plus nivolumab: updated safety across all tumor cohorts and efficacy in advanced bladder cancer

Jason Luke*,Josep Tabernero,Karen Gelmon,Andrea Varga,Victor Moreno,Jayesh Desai,Ben Markman,Carlos Gomez-Roca,Filippo De Braud,Sandip Patel,Matteo Carlino,Lillian Siu,Giuseppe Curigliano,Zhaohui Liu,Yuko Ishii,Megan Wind-Rotolo,Paul Basciano,Alex Azrilevich,Anthony Joshua

The Journal of Urology（2019）

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摘要

INTRODUCTION AND OBJECTIVES:Nivolumab (nivo; anti-PD-1) has shown durable responses and manageable safety (ORR, 19.6%; gr 3-4 treatment-related AEs [TRAEs], 18%) in advanced bladder cancer (advBC [...

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