Cross Validation of the Monoclonal Antibody Das-1 in Identification of High-risk Mucinous Pancreatic Cystic Lesions.

Koushik K Das,Xin Geng,Jeffrey W Brown,Vicente Morales-Oyarvide,Tiffany Huynh,Ilaria Pergolini,Martha B Pitman,Cristina Ferrone,Mohammad Al Efishat,Dana Haviland,Elizabeth Thompson,Christopher Wolfgang, Anne Marie Lennon,Peter Allen,Keith D Lillemoe,Ryan C Fields,William G Hawkins,Jingxia Liu,Carlos Fernandez-Del Castillo,Kiron M Das,Mari Mino-Kenudson

Gastroenterology（2019）

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摘要

We validated the ability of an ELISA with the monoclonal antibody Das-1 to detect PCLs at risk for malignancy with high levels of sensitivity and specificity. This biomarker might be used in conjunction with clinical guidelines to identify patients at risk for cancer.

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关键词

Intraductal Papillary Mucinous Neoplasm (IPMN),Mucinous Cystic Neoplasm (MCN),Pancreatic Cancer,mAb Das-1

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