ESAT-6 modulates Calcimycin-induced autophagy through microRNA-30a in mycobacteria infected macrophages

Assirbad Behura
Assirbad Behura
Abtar Mishra
Abtar Mishra
Saurabh Chugh
Saurabh Chugh
Shradha Mawatwal
Shradha Mawatwal
Ashish Kumar
Ashish Kumar
Debraj Manna
Debraj Manna
Rohan Dhiman
Rohan Dhiman

The Journal of infection, Volume 79, Issue 2, 2019, Pages 139-152.

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Keywords:
3-MA, 3-MethyladenineAtg, Autophagy-related geneAutophagyBaf-A1, Bafilomycin A1CFP-10, Culture filtrate protein of 10 kDaMore(28+)

Abstract:

Taken together, our result evidently highlights that rESAT-6 enhances intracellular survival of mycobacteria by modulating miR-30a-3p and miR-30a-5p expression.

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