Renin-angiotensin system activation and imbalance of matrix metalloproteinase-9/tissue inhibitor of matrix metalloproteinase-1 in cold-induced stroke.
Life Sciences（2019）
摘要
•AngII-mediated MMP-9 expression in response to cold exposure•The imbalance of MMP-9/TIMP-1 play a critical role in the initiation of cold-induced stroke•By inhibit MMP-9 to alleviate MMP-9/TIMP-1 imbalance exert an prevention effect against cold-induced stroke
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关键词
2-Kidney,2-Clip,Angiotensin II,Captopril,rhTIMP-1,Cold exposure
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