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Caveolae set levels of epithelial monolayer tension to eliminate tumor cells

bioRxiv, pp.632802-33, (2019)

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Abstract

Mechanical tension governs epithelial morphogenesis and homeostasis, but its regulation remains poorly understood. Tension is commonly contractile, arising when the actomyosin cortices of cells are mechanically coupled together by cadherin adhesion. Here we report that caveolae control levels of epithelial tension and show that this is ne...More

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Jessica L. Teo
Jessica L. Teo
Ivar Noordstra
Ivar Noordstra
Lakshmi Balasubramaniam
Lakshmi Balasubramaniam
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