Brain-Behavior Phenotypes In 22q11.2 Deletion Syndrome, Idiopathic Psychosis And A Mouse Model

Raquel Gur,Sunny Tang,Monica Calkins,David Roalf,Eric Schmitt,Douglas Coulter,Ruben Gur

BIOLOGICAL PSYCHIATRY（2019）

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摘要

The 22q11DS, associated with 25% risk for psychosis, can be a model for idiopathic psychosis. Prospective studies are needed to examine brain-behavior features and developmental course leading to psychosis. Probing brain circuitry in a mouse model can elucidate underlying deficits.

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关键词

Clinical High Risk For Psychosis, 22q11 Deletion Syndrome, Brain Imaging

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