Gem-Diethyl Pyrroline Nitroxide Spin Labels: Synthesis, Epr Characterization, Rotamer Libraries And Biocompatibility

The Front Cover shows an artistic view of E.coli cells and two spin-labeled recombinantly produced proteins, which can be inserted into the cells via osmotic shock or electroporation methods. The primary sequence of the proteins is schematically shown with the one-letter amino acid code, and cysteine residues are functionalized with the two new gem diethyl nitroxide spin labels designed to better sustain the reducing cellular environment. More information can be found in the Full Paper by S. Bleicken et al.