Creatine supplementation exacerbates ethanol-induced hepatic damage in mice

Poliana Camila Marinello,P.S. Cella, M.T.J. Testa, P.B. Guirro,W.A.S. Brito,F.H. Borges,R. Cecchini,A.L. Cecchini,J.A. Duarte,R. Deminice

Nutrition（2019）

引用 6|浏览13

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摘要

•Creatine supplementation exacerbates the hepatic toxic effects of ethanol.•Creatine intake associated with ethanol upregulates ethanol metabolism genes.•Creatine supplementation exacerbates ethanol-induced oxidative liver damage.•Creatine associated with ethanol intake upregulates inflammation-related genes.•Creatine supplementation exacerbates ethanol-induced liver fat accumulation.

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关键词

Alcoholic liver disease,Inflammation,Oxidative stress,Hepatic injury,Creatine

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