Low 68Ga-PSMA PET/CT Uptake in Chronic Intramuscular Nodular Fasciitis.

Nodular fasciitis is an uncommon benign mass-forming myofibroblastic proliferation, most frequently found in the upper limbs, with only rare intramuscular cases. We describe herein a case of chronic nodular fasciitis of the left triceps muscle with a low Ga-68-labeled prostate-specific membrane antigen (PSMA) ligand uptake on PET/CT. Ga-68-PSMA ligands bind to PSMA-expressing prostate cancer cells, but uptake has also been demonstrated in other solid neoplasms and various benign lesions. Nodular fasciitis should be included in the differential diagnosis of soft tissue lesions with variable Ga-68-PSMA uptake.