Clinical study of medication-related osteonecrosis of the jaw in our department

Medication-related osteonecrosis of the jaw(MRONJ) is a severe adverse event of antiresorptive therapy with bisphosphonate and denosmab and antiangiogenic therapy with VEGF inhibitors. We treated patients with MRONJ in accordance with the recommendations of the Position Paper published by the American Association of Oral and Maxillofacial Surgeons in 2007. To investigate whether the treatment protocol is optimal, we studied a series of patients with MRONJ treated in Yamaguchi University Hospital and report our clinical findings.