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LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling.

EMBO JOURNAL, no. 17 (2019)

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Abstract

Hepatocellular carcinoma (HCC) is the most prevalent liver cancer, characterized by a high rate of recurrence and heterogeneity. Liver cancer stem cells (CSCs) may well contribute to both of these pathological properties, but the mechanism underlying their self-renewal maintenance is poorly understood. Here, we identified a long noncoding...More

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