Serine Protease Inhibitor AEBSF Reduces Dengue Virus Infection via Decreased Cholesterol Synthesis.

Liji Sreelatha,Shilu Malakar,Pucharee Songprakhon,Atthapan Morchang,Chatchawan Srisawat,Sansanee Noisakran, Pa-Thai Yenchitosomanus,Thawornchai Limjindaporn

Virus Research（2019）

引用 8|浏览22

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摘要

•AEBSF decreases dengue viral RNA replication and protein synthesis.•AEBSF inhibits dengue virus production of all four serotypes.•Anti-DENV property of AEBSF is attributed to its ability to decrease intracellular cholesterol.

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关键词

Serine protease inhibitor,AEBSF,Dengue virus infection,Cholesterol synthesis

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