Circulating Serpina3 levels predict the major adverse cardiac events in patients with myocardial infarction.

•Plasma Serpina3 levels are elevated in AMI compared with healthy controls.•Total cholesterol and ESR are independent factors for Serpina3.•AMI patients with lower Serpina3 levels have an increased event-free survival rate.•Serpina3 can be a predictor of MACE in AMI.