Inflammatory neuropathology of infantile Alexander disease: A case report.

Kengo Kora,Takeo Kato,Minako Ide,Takayuki Tanaka,Tomokatsu Yoshida

Brain and Development（2020）

引用 4|浏览9

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摘要

These results suggest that inflammatory responses of astrocyte and microglia can contribute to the neuropathology of AxD. Robust immunomodulation that targets activated astrocytes and microglia may be a novel therapeutic strategy to improve neurological prognosis in AxD.

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关键词

Alexander disease,Neuroinflammation,Macrophage chemotactic protein 1,Astrocyte,Steroid pulse therapy

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