Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis.
The Journal of Steroid Biochemistry and Molecular Biology（2019）
Abstract
•hCG signaling pathway regulates Fxrα expression.•cAMP signaling pathway regulates Fxrα expression.•FXRα agonist exposure leads to a negative feedback of the hCG-induced steroid synthesis.
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Key words
Leydig,Testis,hCG signaling,FXRα,Steroidogenesis
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