Comparative Efficacy of Treatment Options for Minimal Hepatic Encephalopathy: A Systematic Review & Network Meta-analysis.

Radha K Dhiman,Kiran K Thumburu,Nipun Verma,Madhu Chopra,Sahaj Rathi,Usha Dutta,Ashwani K Singal,Sunil Taneja,Ajay Duseja,Meenu Singh

Clinical Gastroenterology and Hepatology（2020）

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摘要

Rifaximin and lactulose were most effective for reversal of minimal HE. L-Ornithine L-Aspartate and lactulose were most effective in prevention of overt HE. Lactulose was the only agent effective in reversing minimal HE, preventing overt HE, reducing ammonia and improving quality of life; but with tolerable adverse effects. (PROSPERO-ID:107003).

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Hepatic Insufficiency,Cognition,Chronic Liver Disease,Antibiotic

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