Antibiotic exposure disturbs the gut microbiota and its metabolic phenotype differently in rats with advanced-stage type 1 diabetes and age-matched controls

Hong Zheng
Hong Zheng
Hui Ji
Hui Ji
Qiaoying Jiang
Qiaoying Jiang
Jie Ning
Jie Ning
Pengtao Xu
Pengtao Xu
Chen Li
Chen Li

JOURNAL OF PROTEOME RESEARCH, pp. 3944-3954, 2019.

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Abstract:

Antibiotic-induced microbial perturbations alter host metabolism and affect host physiology. In this study, we aimed to investigate the effects of vancomycin (Vanc) and ciprofloxacin/metronidazole (CiMe) exposures on the gut microbiome and metabolome in the colonic content and tissue samples from advanced-stage type 1 diabetic (AST1D) rat...More

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