Enantioselective resolution of biologically active dipeptide analogs by high-performance liquid chromatography applying Cinchona alkaloid-based ion-exchanger chiral stationary phases.

•Use of chiral ion-exchangers for the separation of dipeptides is demonstrated.•Enantio- and diastereoselectivity of Cinchona alkaloid-based selectors are evaluated.•Structure-retention relationships are qualitatively discussed.