Trend in the Prevalence of Diabetes between 2002-2009 in Populations in Qingdao, China

The current study aims to determine the secular trend of prevalence of type 2 diabetes and prediabetes and risk factors for diabetes from 2002 to 2009. We conducted 3 population-based surveys for diabetes in individuals aged 35-74 years in Qingdao in 2002, 2006 and 2009, respectively, with random-sampling approach. The sample size was 1792, 4549 and 4310 in 2002, 2006 and 2009, respectively. We performed a questionnaire-based survey to collect general information. All participants underwent standardized 2-h 75-g oral glucose tolerance tests (OGTTs). The 1999 WHO diagnostic criteria for diabetes and prediabetes was applied. Age-standardized prevalence of diabetes was calculated. Multiple non-conditional logistic regression were applied to analyze the risk factors for diabetes, taking diabetes as the dependent variable. In 2002, the age-standardized prevalence of diabetes was 12.32%, the corresponding prevalence was 16.57% and 18.01%, respectively, in 2006 and 2009. The prevalence of diabetes increased from 2002 to 2009 (p<0.05). The age-standardized prevalence of prediabetes in 2002, 2006 and 2009 was 16.18%, 24.56% and 28.25%, respectively (P for trend < 0.05). Multiple non-conditional logistic regression analysis showed that the risk factor for diabetes were age, waist, systolic blood pressure (SBP), total cholesterol, triglyceride, and family history of diabetes in both 2002 and 2006. The risk factor for diabetes included age, waist, SBP, total cholesterol, triglyceride, and family history of diabetes in 2009. High density lipoprotein cholesterol was negatively associated with increased risk for diabetes. The prevalence of diabetes and prediabetes in Qingdao increases from 2002 to 2009, implying an epidemic of diabetes in this area. The common risk factors contributing to the increasing trend are age, waist, SBP, total cholesterol, triglyceride, and family history of diabetes. Disclosure L. Zhang: None. W. Gao: None. N. Wang: None. J. Wang: None. X. Yin: None. Y. Zhu: None. Y. Dong: None.