A convenient synthesis of 8-alkyl-2' (or 3')-azido (or amino)-2' (or 3')-deoxyadenosine as diverse synthetic precursors of cyclic adenosine diphosphate ribose (cADPR)

BULLETIN OF THE KOREAN CHEMICAL SOCIETY, pp. 986-990, 2006.

Cited by: 2|Bibtex|Views0|DOI:https://doi.org/10.5012/bkcs.2006.27.7.986
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Abstract:

key nucleoside intermediates for the preparation of cyclic adenosine diphosphate ribose (cADPR, 1) analogues, 8-alkyl-2' (or 3')-azido(or amino)-adenosine derivatives (16-19) were successfully prepared by alkylating selectively protected adenosine derivatives (12, 13) via Pd(0) catalyzed cross-coupling reaction with tetraalkyltin reagents...More

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