Synthesis of Phenolic Components of Grains of Paradise
Tetrahedron letters(2019)
摘要
Two vanilloids, (5E)-8-(4-hydroxy-3-methoxyphenyl)oct-5-en-4-one (1) and 4-[3-hydroxydecyl]-2-methoxyphenol (2), isolated from the dried seeds of Grains of Paradise (Aframomum melegueta), were synthesized; the latter compound was made as the S-enantiomer and the material derived from the seeds was found to be a 1:1.7 mixture of the R and S isomers. The synthetic route used should allow the preparation of analogs having extended alkyl chains and consequently different lipophilicity, and 3, a homolog of 2, was also prepared. (C) 2019 Elsevier Ltd. All rights reserved.
更多查看译文
关键词
Grains of Paradise,Anti-obesity,Malic acid,Wittig reaction,Horner-Wadsworth-Emmons olefination,Hydrogenolysis
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要