New mouse models of melanoma metastasis and differences in brain tropism and metastatic growth pattern.

Amr M. Morsi, Avital Gazial-Sovran, Hana Baig,Robert S. Kerbel,John Golfinos,Youssef Zaim Wadghiri,Eva Hernando

Journal of Clinical Oncology（2017）

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摘要

e19015 Background: 75% of patients with metastatic melanoma develop brain metastases (B-mets). Such patients show dismal prognosis with a median survival of < 6 months. Scarcity of clinically relev...

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