Dicaffeoylquinic acids from Ilex kudingcha attenuate dextran sulfate sodium-induced colitis in C57BL/6 mice in association with the modulation of gut microbiota

Peng Wan,Yujia Peng,Guijie Chen,Minhao Xie,Zhuqing Dai,Kaiyin Huang,Wei Dong,Xiaoxiong Zeng,Yi Sun

Journal of Functional Foods（2019）

引用 19|浏览11

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摘要

•Dicaffeoylquinic acids (DiCQAs) from Ilex kudingcha attenuated DSS induced colitis.•DiCQAs enhanced gut barrier integrity and decreased inflammatory cytokines.•DiCQAs increased short chain fatty acids and modulated the gut microbiota.•DiCQAs attenuated colitis may through regulating the 5 key gut bacteria.

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关键词

Ilex kudingcha,Dicaffeoylquinic acids,Colitis,Inflammation,Gut microbiota,Short-chain fatty acids

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