A Structure-Guided Molecular Chaperone Approach for Restoring the Transcriptional Activity of the P53 Cancer Mutant Y220C
Future Medicinal Chemistry（2019）
Key words
cancer mutations,cancer therapy,CRISPR/Cas9 p53 knockout,molecular chaperones,p53,protein stabilization,structure-based drug design,tumor suppression
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined