Treatment of Patients With Relapsed/Refractory Non-Hodgkin Lymphoma With Venetoclax: A Single-Center Evaluation of Off-Label Use.
Clinical Lymphoma Myeloma and Leukemia(2019)
摘要
Venetoclax therapy in a real-world cohort offered modest benefits in heavily pretreated patients. Adverse events were observed at a greater incidence than in the clinical trials. A wide heterogeneity of venetoclax dose escalation, multiagent combinations, and timing of initiation were identified and require investigation in subsequent clinical trials.
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关键词
Aggressive lymphoma,Antineoplastic agents,Outcomes,Pharmacotherapy,Targeted therapy
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