Role of CX3CR1 Signaling in Malignant Transformation of Gliomas

NEURO-ONCOLOGY(2020)

引用 22|浏览45
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摘要
CX3CR1 V249I polymorphism is associated with improved overall and progression-free survival in LGGs. CX3CR1 signaling enhances accumulation of tumor associated microglia/macrophages and angiogenesis during malignant transformation.
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关键词
CX3CR1,glioma,malignant transformation,polymorphism,tumor microenvironment
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