Dose and Volume De-Escalation for Human Papillomavirus-Positive Oropharyngeal Cancer is Associated with Favorable Post-Treatment Functional Outcomes.

Corey C Foster,Tanguy Y Seiwert,Ellen MacCracken,Elizabeth A Blair,Nishant Agrawal,James M Melotek,Louis Portugal,Ryan J Brisson,Zhen Gooi,Michael T Spiotto,Everett E Vokes,Daniel J Haraf

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2020）

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摘要

Induction chemotherapy followed by risk- and response-adapted dose and volume de-escalated RT/CRT is associated with clinically meaningful functional outcomes including (1) improved swallowing function, (2) higher BMI, and (3) shorter narcotic use for patients receiving de-escalation.

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关键词

papillomavirus–positive oropharyngeal cancer,human papillomavirus–positive,de-escalation

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