Prevention and control of meningococcal disease: updates from the Global Meningococcal Initiative in Eastern Europe.

Journal of Infection(2019)

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摘要
•Incidence of IMD has declined and surveillance is in place in most Eastern European countries.•Predominating serogroups of Nm are B and C, then A; W, Y and X are emerging.•Vaccines are not in NIPs/only provided to high-risk groups, in which antibiotic prophylaxis is key.•Use of conjugate vaccines is recommended to interrupt acquisition of carriage.•Monitoring outbreaks, spread of Nm and antibiotic resistance can inform management strategies.
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关键词
Antibiotic resistance,Bacterial meningitis,Conjugate vaccine,Eastern Europe,High-risk groups,Immunization program,Meningococcal disease,Neisseria meningitidis,Polysaccharide vaccine,Refugees
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