Proteomic, metabolic and immunological changes in Biomphalaria glabrata infected with Schistosoma mansoni

Tiago Manuel Fernandes Mendes,Emanuel Carrilho,Ana Júlia Pinto Fonseca Sieuve Afonso,Carlos Alexandre Galinaro,Fernanda Janku Cabral,Silmara Marques Allegretti

International Journal for Parasitology（2019）

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摘要

•Schistosoma mansoni infection causes an increase in Biomphalaria glabrata energy requirements.•An increase in energy requirements leads to an increase in alternative metabolic pathways.•After infection, several proteins with potential immunological roles were up-regulated.•Two proteins with potential immunological roles were found to be down-regulated.

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关键词

Biomphalaria glabrata,Immune response,Metabolism,Proteomics,Schistosoma mansoni

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