Adapting the psychological mediation framework for cisgender and transgender sexual minorities in Jamaica: Implications from latent versus observed variable approaches to sexual stigma.

•Research examining pathways from sexual stigma dimensions to depression is limited.•Applied the psychological mediation framework with sexual minorities in Jamaica.•Tested a latent sexual stigma construct and sexual stigma dimensions separately.•Sexual stigma reduced social support and resilient coping to increase depression.•Multiple approaches to sexual stigma measurement can inform interventions.