The challenges of tuberculosis control in protracted conflict: the case of Syria

•The conflict has decimated Syria’s health system, destroying key infrastructure.•The extent of tuberculosis (TB) in Syria, particularly the extent of drug resistance is unknown.•Addressing TB among vulnerable populations is key to TB control in Syria.•Failure to address TB within Syria’s borders impacts refugee destination countries.•Innovative measures for case finding, diagnosis, and management in conflict are needed.