Disparity in clinical outcomes between pure and combined pulmonary large-cell neuroendocrine carcinoma: A multi-center retrospective study

Jia-Tao Zhang,Ye Li,Li-Xu Yan,Zheng-Fei Zhu,Xiao-Rong Dong,Qian Chu,Lin Wu,Hong-Mei Zhang,Chun-Wei Xu,Gen Lin,Zong-Yang Yu,Jie Hu,Bo Zhu,Hui-Juan Wang,Fan Yang,Zheng-Bo Song, Zheng-Bo Han,Meng-Xia Li,Jie Lin,Yi-Long Wu

Lung Cancer（2020）

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摘要

•Syn, CgA and CD56 were related to the prognosis of LCNEC.•Adenocarcinoma was the most common combined components for LCNEC.•SCLC chemotherapy regimen is a more effective choice for LCNEC.•Overall survival of combined LCNEC tended to be shorter than pure LCNEC.

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Cancer epidemiology

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