Behavioral Characteristics of 5-HT 2C Receptor Knockout Mice: Locomotor activity, Anxiety-, and Fear Memory-related Behaviors.

Mao Nebuka,Yu Ohmura,Shuntaro Izawa,Youcef Bouchekioua,Naoya Nishitani,Takayuki Yoshida,Mitsuhiro Yoshioka

Behavioural Brain Research（2020）

引用 14|浏览19

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摘要

•5-HT2C receptor knockout mice displayed slower habituation to a novel environment.•5-HT2C receptor knockout produced an anxiolytic phenotype.•5-HT2C knockout might facilitate within-session extinction of contextual fear.•Our findings provided reasonable explanations about previous inconsistent findings.

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关键词

Htr2c,5-HT1C,Motor activity,Freezing behavior

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