Atomoxetine Reestablishes Long Term Potentiation in a Mouse Model of Attention Deficit/Hyperactivity Disorder.

Ricardo Piña,Carlos Rozas,Darwin Contreras,Paulina Hardy,Gonzalo Ugarte,Marc L Zeise,Patricio Rojas,Bernardo Morales

Neuroscience（2020）

引用 17|浏览19

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摘要

•An ADHD murine model, display an hyperactive phenotype and a reduced hippocampal LTP.•Atomoxetine reestablishes normal behavior and spatial working memory in this model.•Atomoxetine also reestablishes normal hippocampal synaptic plasticity, LTP.

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关键词

LTP,ADHD,Atomoxetine,Prenatal nicotine,hippocampus,norepinephrine

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