Neutrophil membranes coated, antibiotic agent loaded nanoparticles targeting to the lung inflammation.

Kaiyu Wang,Yiteng Lei,Donglin Xia,Peipei Xu,Tao Zhu, Zhongying Jiang,Yuqiang Ma

Colloids and Surfaces B: Biointerfaces（2020）

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摘要

•Antibiotic drug loaded nanoparticles coated with neutrophil membranes (NM-NP-SPX) were developed.•NM-NP-SPX had the abilities of controlled-release and biocompatibility.•NM-NP-SPX could precisely target to the sites of inflammation.•NM-NP-SPX could cure pneumonia effectively without any side effects.

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关键词

Nanoparticles,Neutrophil membrane,Inflammation,Sparfloxacin,Pneumonia

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