Curcumin induced photodynamic therapy mediated suppression of quorum sensing pathway of Pseudomonas aeruginosa: An approach to inhibit biofilm in vitro.

•Curcumin mediated APDT shows better bacteriostatic than bactericidal activity.•The thickness of biofilms was reduced from >30 μm to <5 μm after APDT.•Singlet oxygen is primarily responsible for cytotoxic reactions caused by APDT.•The inhibition was due the downregulation of quorum sensing mechanism.•This in turns wipes out EPS that helps in biofilm formation.